It was nearly a century ago, in the midst of the quantum and relativistic revolutions in physics, that Whitehead realized scientific progress had reached a turning point:

The old foundations of scientific thought are becoming unintelligible. . . . What is the sense of talking about a mechanical explanation when you do not know what you mean by mechanics? If science is not to degenerate into a medley of ad hoc hypotheses, it must become philosophical and must enter upon a thorough criticism of its own foundations. (SMW 24)

Despite Whitehead's warning, the 1920s also saw the rise of a positivist prohibition on speculative metaphysics, handicapping progress into the foundations of postclassical science and producing precisely the fragmented medley that he feared. Fortunately, a growing chorus of interdisciplinary scientists is taking up the philosophical work left unfinished by the early-twentieth-century founders of quantum theory. In Untying the Gordian Knot:...

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