The problem of mental causation epitomizes problems in the metaphysics of mind. Tyler Burge once suggested that it could be solved by taking ordinary explanatory practice more seriously. Jaegwon Kim criticized this suggestion: a solution to the problem requires a workable metaphysics of mental causation, and taking ordinary explanatory practice seriously falls short of providing that. Burge replied by gesturing toward a metaphysics that takes mental and physical causation to be different, noncompeting forms of causation. But what does it mean for there to be different forms of causation? How are they identified and distinguished? And what ensures that mental and physical causation are different and noncompeting? I attempt to answer these questions by appeal to hylomorphism, a metaphysical framework that takes structure to be a basic ontological and explanatory principle. I argue that hylomorphism enables us to develop Burge’s basic insights into a workable metaphysics of mental causation that solves the problem.