Logistics reconfiguration is an active practice in the Chinese pharmaceutical industry. However, the reconfiguration performances are not satisfactory. This article investigates logistics reconfiguration strategies and develops a logistics reconfiguration success framework by a three-stage multi-method research approach. Telephone interviews and qualitative case study research methodology are used to collect data. From case studies, nine key success factors are identified. These factors are further validated as being relevant by a group of senior managers from industry. Finally, managerial implications are drawn.