Luther’s first Psalms lectures frequently cite the early medieval commentator, Cassiodorus. At the outset of his second Psalms lectures, Luther distances himself from Cassiodorus’s exegetical approach due to the nonliteral nature of his exegesis. Nevertheless, comparisons of selected Psalms writings by the two men demonstrate an ongoing, deep-seated similarity; Luther maintains with Cassiodorus a reading of Psalms which is thoroughly formational, urging that Psalms exegesis necessarily culminate in prayer. I will suggest that features ingredient to the Psalter, not foreign thereto, motivate this exegetical impulse for both interpreters. Finally, the study will conclude by briefly proposing implications for contemporary theological interpretation of the Psalter.