The idea behind right and wrong is premised on ethics. There have been controversies about the philosophy of right and wrong in Western and African thoughts. There is a perception that the essential difference between right and wrong is honor-orientation versus justice-orientation, which is believed to be based on shame and guilt. With the aforementioned, the researcher sought to explore the comparative analysis on guilt and shame in Western and African ethics using a qualitative research design to make the investigation. It was discovered that Western ideas and beliefs are quite different from those of African society. Western ethical standards have been used wrongly to scan African ethics and ethical conducts and these African ethical conducts have not been given elaborate investigation and clarification. It concluded that using Western ethical standards to judge African moral ideas is biased and demeaning to philosophical scholarship. Some recommendations on extensive analysis and interpretation of moral values on the scale of guilt and shame as well as a rethink on morality as it relates to ethics and corporate existence were made.