Few will dispute that the sciences were of special importance to Nietzsche. The natural and human sciences had a significant influence on his thought from the very beginning, and his writings probe and engage with them, exploring their interrelations as well as their place in an adequate broader view of our existence. By contrast, it is less clear whether Nietzsche had, or thought that we could have, something that amounts to a philosophy of science. To the extent that he did, we must ask what its content and value may be. This involves asking whether his thought can help to explain what natural science is, what it can and cannot do, and how it relates to other areas of enquiry. Similarly, we must ask how it can help us to further not only the concerns of humanistic understanding but also our understanding of these concerns themselves.

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